Double bar chart - Nitrate concentration in Community Water Systems (CWS)

This double bar chart sample shows the nitrate concentration in milligrams per liter in Community Water Systems (CWS), mean and maximum by year, in New Mexico in 1999-2015. It was drawn using data from the New Mexico's Indicator-Based Information System (NM-IBIS) website. [ibis.health.state.nm.us/ indicator/ complete_ profile/ CommWaterNitrates.html]
"Nitrate toxicity is a preventable cause of methemoglobinemia (blue baby syndrome), especially in infants. Infants younger than 4 months of age are at greatest risk of toxicity from nitrate-contaminated drinking water.
These infants are more susceptible to developing methemoglobinemia because the pH of their gut is normally higher (less acidic) than in older children and adults. The higher pH enhances the conversion of ingested nitrate to the more toxic nitrite. The bacterial flora of a young infant's gut is also different from that found in older children and adults and might be more likely to convert ingested nitrate to nitrite. Gastroenteritis can increase body transformation of nitrate to nitrite and absorption into the bloodstream of nitrite from the large intestine.
A large proportion of hemoglobin in young infants is in the form of fetal hemoglobin. Fetal hemoglobin is more readily oxidized to methemoglobin (MHg) by nitrites than is adult hemoglobin. In addition, in infants, the enzyme (NADH-dependent methemoglobin reductase) responsible for reduction of formed MHg back to normal hemoglobin has only about half the activity it has in adults.
Symptoms such as shortness of breath and bluish skin coloring around the mouth, hands, or feet, can occur in infants rapidly over a period of days. If the condition is severe, it could lead to convulsions, coma, and even death, if untreated. Most older children and adults can take in larger amounts of nitrate without experiencing the same health effects as infants. However, pregnant women, nursing mothers, and people with low stomach acid conditions or those deficient in an enzyme that changes MHg back to normal hemoglobin are more susceptible to nitrate-induced methemoglobinemia and could be affected by water with nitrate levels above 10 mg/ L.
Adverse reproductive outcomes such as spontaneous abortions, intrauterine growth retardation, and various birth defects such as anencephaly have been reported in scientific literature from exposure to high nitrate levels in drinking water; however, the evidence is inconsistent.
Little is known about possible health effects from high nitrate level exposure over a long period of time. However, some studies suggest that there might be a risk of stomach, esophageal or bladder cancers in people with prolonged ingestion of high levels of nitrate. This might be due to the formation of nitrosoamines in the body following ingestion exposure to high levels of nitrate.
International Agency for Research on Cancer (IARC) classified ingested nitrate or nitrite as probably carcinogenic to humans (Group 2A) under conditions that result in formation of nitroso-compounds (e.g., nitrosoamines) in the body (endogenous nitrosation)." [ibis.health.state.nm.us/ indicator/ view/ CommWaterNitrates.MeanMax.Year.html]
The column chart example "Nitrate concentration in Community Water Systems (CWS)" was created using the ConceptDraw PRO diagramming and vector drawing software extended with the Bar Graphs solution from the Graphs and Charts area of ConceptDraw Solution Park.

The vector stencils library "Carbohydrate metabolism" contains 25 icons of metabolite symbols.
Use these shapes for drawing carbohydrate metabolism schematics, biochemical diagrams and metabolic pathways maps.
"Carbohydrates are a superior short-term fuel for organisms because they are simpler to metabolize than fats or those amino acids (components of proteins) that can be used for fuel. In animals, the most important carbohydrate is glucose. The concentration of glucose in the blood is used as the main control for the central metabolic hormone, insulin. Starch, and cellulose in a few organisms (e.g., some animals ... and ... microorganisms), both being glucose polymers, are disassembled during digestion and absorbed as glucose. Some simple carbohydrates have their own enzymatic oxidation pathways, as do only a few of the more complex carbohydrates. The disaccharide lactose, for instance, requires the enzyme lactase to be broken into its monosaccharides components; many animals lack this enzyme in adulthood." [Carbohydrate metabolism. Wikipedia]
The shapes example "Design elements - Carbohydrate metabolism" is included in the Biology solution from the Science and Education area of ConceptDraw Solution Park.

The vector stencils library " Biochemistry of metabolism" contains 46 metabolite symbols for drawing metabolic pathways maps, biochemical diagrams and metabolism process flow charts using the ConceptDraw PRO diagramming and vector drawing software.
"Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. ...
The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions." [Metabolite. Wikipedia]
The shapes example "Design elements - Biochemistry of metabolism" is included in the Biology solution from the Science and Education area of ConceptDraw Solution Park.

"Tryptophan (IUPAC-IUBMB abbreviation: Trp or W; IUPAC abbreviation: L-Trp or D-Trp; sold for medical use as Tryptan) is one of the 22 standard amino acids and an essential amino acid in the human diet, as demonstrated by its growth effects on rats. It is encoded in the standard genetic code as the codon UGG. Only the L-stereoisomer of tryptophan is used in structural or enzyme proteins, but the R -stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). The distinguishing structural characteristic of tryptophan is that it contains an indole functional group." [Tryptophan. Wikipedia]
The chemical drawing example "Tryptophan molecule ball-and-stick model" was created using the ConceptDraw PRO software extended with the Chemistry solution from the Science and Education area of ConceptDraw Solution Park.

"In biochemistry, metabolic pathways are series of chemical reactions occurring within a cell. In each pathway, a principal chemical is modified by a series of chemical reactions. Enzymes catalyze these reactions, and often require dietary minerals, vitamins, and other cofactors in order to function properly. Because of the many chemicals (a.k.a. "metabolites") that may be involved, metabolic pathways can be quite elaborate. In addition, numerous distinct pathways co-exist within a cell. This collection of pathways is called the metabolic network. Pathways are important to the maintenance of homeostasis within an organism. Catabolic (break-down) and Anabolic (synthesis) pathways often work interdependently to create new biomolecules as the final end-products." [Metabolic pathway. Wikipedia]
The biochemical diagram example "Metabolic pathway map" was created using the ConceptDraw PRO diagramming and vector drawing software extended with the Biology solution from the Science and Education area of ConceptDraw Solution Park.